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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY3
All Species:
18.48
Human Site:
S545
Identified Species:
40.67
UniProt:
O60266
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60266
NP_004027.2
1144
128960
S545
A
H
S
S
G
S
T
S
E
K
P
E
E
Q
D
Chimpanzee
Pan troglodytes
XP_001146938
1144
128907
S545
A
H
S
S
G
S
T
S
E
K
P
E
E
Q
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849405
1146
129117
S545
I
H
T
S
G
S
T
S
E
E
P
E
E
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHH7
1145
129024
S544
A
H
A
S
G
S
T
S
E
E
A
E
E
Q
E
Rat
Rattus norvegicus
P21932
1144
128917
S543
A
H
A
S
G
S
T
S
E
E
A
E
E
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516134
489
54212
Chicken
Gallus gallus
Q9DGG6
1334
149273
C623
S
T
T
L
V
P
P
C
D
V
S
I
D
E
G
Frog
Xenopus laevis
P98999
1305
145393
T618
T
N
C
T
Q
P
E
T
L
K
S
C
P
S
C
Zebra Danio
Brachydanio rerio
NP_001156014
1071
120992
R509
N
P
S
F
P
N
P
R
R
R
L
R
L
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610116
1167
130377
I538
S
V
S
N
G
H
Q
I
G
I
A
V
T
A
D
Honey Bee
Apis mellifera
NP_001071276
998
110837
P455
R
A
L
K
P
F
I
P
A
V
T
K
S
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.7
N.A.
94.2
94.4
N.A.
34
25.2
27.9
72.3
N.A.
37.9
39.2
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
96.8
N.A.
97.2
97.3
N.A.
37.5
43.1
44.8
82.6
N.A.
55.8
56.3
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
73.3
73.3
N.A.
0
0
6.6
13.3
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
33.3
26.6
33.3
N.A.
33.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
19
0
0
0
0
0
10
0
28
0
0
10
10
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
46
% D
% Glu:
0
0
0
0
0
0
10
0
46
28
0
46
46
10
19
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
55
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
46
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
10
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
28
0
10
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
10
0
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
19
19
19
10
0
0
28
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
0
46
0
% Q
% Arg:
10
0
0
0
0
0
0
10
10
10
0
10
0
10
0
% R
% Ser:
19
0
37
46
0
46
0
46
0
0
19
0
10
10
0
% S
% Thr:
10
10
19
10
0
0
46
10
0
0
10
0
10
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
19
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _